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Morfin er et naturligt stof fra valmuens frøkapsel. Det er den mest aktive og stærkest virkende del af valmuen. Gennem kemiske processer kan person bearbejde morfinen til det ulovlige stof heroin.De syntetiske opioider petidin og fentanyl virker på de samme modtagere i nervesystemet som morfin, og de ligner morfin i deres virkning og bivirkninge
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